VESPER-RCT
Venous Excess Ultrasound (VEXUS)-Guided Fluid Management versus Usual Care in Patients with Septic Shock: a pilot RCT study
PI: Dr. John Basmaji (pager 19069)
Lead Investigator: Dr. Diyaa Bokhary (pager 14405)
Embedded Files
Eligibility Criteria
Eligibility Criteria
Inclusion Criteria:
Within 16 hours of meeting Sepsis-3 definition:
- Vasopressor requirement to maintain MAP ≥65 mmHg.
- Lactate >2 mmol/L.
- Suspected/ confirmed infection.
Exclusion Criteria:
Any of the following:
- Already on or planned for RRT.
- Goals-of-care limitations.
- Active bleeding or on ECMO\IABP.
- Cirrhosis, severe TR, or anatomical barriers to ultrasound (e.g.: nonremovable surgical dressings).
- Post-cardiac arrest or liver\kidney transplant patients.
- Severe metabolic/electrolyte derangements (e.g.: K <3, Na >155)
- Inability to measure fluid balance accurately.
Summary of the research idea
Summary of the research idea
Page updated
Google Sites
Report abuse